News

A photo of a bespectacled young boy, his red baseball cap slightly askew as he  enjoys time outside, will be featured on the front cover of an upcoming calendar in the “Same But Different” contest to raise awareness about rare disorders. “A Lovely Day Out in Kew Gardens,”…

The incidence and prevalence of most acquired hemolytic disorders, including cold agglutinin disease (CAD), have been rising in Denmark in the past decades, regardless of age and sex, a retrospective study including 36 years of data found. Incidence is the proportion of new cases over a…

A majority of rare disease patients using telehealth during the COVID-19 pandemic thought the experience positive, and many would like the option of continuing its use in future appointments, a series of surveys found. The surveys were conducted by the National Organization for Rare Disorders (NORD) and involved more than 800…

The case of an infant who developed cold agglutinin disease (CAD) shortly after being vaccinated suggests that intravenous immunoglobulin may be an effective treatment for young children with the autoimmune disorder, according to a new report. The report, “Cold agglutinin disease in an infant: remission after intravenous…

Cold agglutinin disease (CAD) may develop as a result of severe COVID-19, further complicating laboratory tests and treatment for these individuals, according to a case report in two patients. The case study, “Cold agglutinin syndrome as a complication of Covid-19 in two cases,” was published…

Same But Different, a nonprofit U.K. group that uses art for social change, is inviting people to choose their favorite photographs in a calendar contest to heighten awareness of rare diseases, including amyotrophic lateral sclerosis (ALS). The organization’s panel of judges has pared the number of contest submissions…

Treatment with the cancer immunotherapy Keytruda (pembrolizumab) can lead to the development of cold agglutinin disease (CAD), the case of a lung cancer patient demonstrates. The report, “Pembrolizumab-Induced Cold Agglutinin Disease,” was published in the American Journal of Case Reports. While the immune system…

Cold agglutinin disease (CAD) seems to be the least common form of autoimmune hemolytic anemia (AIHA) in India, affecting about 15% of patients with the rare disorder, a study has found. The study, “Immunohematological work‐up, severity analysis and transfusion support in autoimmune hemolytic anemia patients,”…

Researchers in the U.K. have described the case of an 81-year-old woman who was diagnosed with secondary cold agglutinin disease (CAD) only after falling and being treated at the hospital for several broken bones. The woman’s fall reactivated a cytomegalovirus…

Physicians should consider testing patients with COVID-19 and thrombosis for different forms of autoimmune hemolytic anemia (AIHA), including cold agglutinin disease (CAD), which may underlie their blood clotting issues, a case report says. In severe cases, doctors should also consider starting treatment for AIHA immediately to…