Few cases of cold agglutinin disease (CAD) secondary to systemic lupus erythematosus, or SLE, have been reported over the past seven decades, but all occurred in women, according to a study by two researchers in Colombia. In addition to describing two new cases of CAD secondary to SLE —…
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Tilting my head upward, I looked to the stars. There it was, the easiest constellation for me to identify: Orion. I identified it by the three stars in a row that make up his belt, and then looked down to his right side — my left — and saw the…
Clinicians detected B-cell lymphoma, a type of blood cancer, in a 53-year-old man two years after he was diagnosed with cold agglutinin disease (CAD) marked by anemia, or low counts of red blood cells, but no symptoms, a case study indicates. All signs of lymphoma and CAD disappeared after…
I’m finding myself weary at the start of every day. Sleep doesn’t provide much calming rest, and I need time to focus myself before I begin any work. That’s frustrating! I want to “get cracking,” but the flesh doesn’t match my spirit. Then I came across a quote online (source…
Cold agglutinin disease (CAD) was the likely cause of blood clot formation during brain surgery in a 57-year-old man, despite measures to prevent his body temperature from getting too low, a case study in Turkey showed. Because the clot occurred at the site where two brain blood vessels were…
Cold agglutinin disease (CAD) is a rare disorder in which the immune system mistakenly attacks red blood cells, resulting in anemia.
CAD is characterized by autoantibodies, called cold agglutinins, binding to and activating the destruction of red blood cells when exposed to cold temperatures.
Symptoms of CAD include fatigue, Raynaud’s syndrome, joint pain, jaundice or skin discoloration, and heart problems. These symptoms can worsen with more cold exposure.
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