I was enveloped in a deliciously warm environment, floating as if on a cloud, bathed in warm sunshine. I stretched out my arm, which immediately whapped against the bedroom wall. My luxurious sleep had ended. I reached down and lifted up my laptop from the bottom shelf of my bedside…
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Very low doses of rituximab rapidly reduced blood levels of disease-driving B-cells in people with cold agglutinin disease (CAD) and other forms of autoimmune hemolytic anemia (AIHA), but this suppression was not consistently sustained over time. Those are the findings of a small pilot Phase 2 clinical…
Warming and an extra dose of corticosteroid medication were part of multiple strategies doctors used to allow for a safe Cesarean section (c-section), without complications, in a pregnant woman with cold agglutinin disease (CAD), according to a case report. The woman was kept warm right during her hospital stay,…
It is a truth universally acknowledged that people with cold agglutinin disease (CAD) can’t breathe. However little known the feelings or views of such a person, this truth is so well-fixed in the minds of the surrounding families, that people with CAD, because they can’t breathe, will never walk…
Cold agglutinin disease (CAD) was the likely trigger of repeated mini-strokes in an 84-year-old woman with already compromised blood flow in the brain due to severe narrowing of a major artery that supplies blood to the brain, according to a case report from Portugal. The underlying mechanisms of red…
Cold agglutinin disease (CAD) is a rare disorder in which the immune system mistakenly attacks red blood cells, resulting in anemia.
CAD is characterized by autoantibodies, called cold agglutinins, binding to and activating the destruction of red blood cells when exposed to cold temperatures.
Symptoms of CAD include fatigue, Raynaud’s syndrome, joint pain, jaundice or skin discoloration, and heart problems. These symptoms can worsen with more cold exposure.
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