News

CAD likely caused blood clot during brain surgery: Case report

Cold agglutinin disease (CAD) was the likely cause of blood clot formation during brain surgery in a 57-year-old man, despite measures to prevent his body temperature from getting too low, a case study in Turkey showed. Because the clot occurred at the site where two brain blood vessels were…

Rituximab treatment effective in combined CAD, autoimmune disease

A man with rheumatoid arthritis and cold agglutinin disease (CAD) achieved complete remission following treatment with rituximab, an antibody-based therapy commonly used off-label for CAD, a recent case study indicates. Rituximab therapy also treated the man’s cooccurring immune thrombocytopenia, an autoimmune disorder marked by the destruction of platelets, which…

Warming part of CAD pain management during C-section

Warming and an extra dose of corticosteroid medication were part of multiple strategies doctors used to allow for a safe Cesarean section (c-section), without complications, in a pregnant woman with cold agglutinin disease (CAD), according to a case report. The woman was kept warm right during her hospital stay,…

Case study notes challenges to CAD diagnosis, care in Pakistan

Researchers said a case of cold agglutinin disease (CAD) in a 92-year-old man in Pakistan illustrates the challenges of CAD diagnosis and management in developing countries. The man’s experience highlights “the urgent need to improve healthcare infrastructure and enhance diagnostic capabilities while facilitating equitable access to essential CAD treatments…