Modified red blood cell products may be better at counteracting anemia than red blood cell suspensions normally used in conventional blood transfusions, while posing fewer side effects to patients with autoimmune hemolytic anemia (AIHA), a review study has found. Yet, investigators noted that additional studies will be needed to…
Physicians should consider testing patients with COVID-19 and thrombosis for different forms of autoimmune hemolytic anemia (AIHA), including cold agglutinin disease (CAD), which may underlie their blood clotting issues, a case report says. In severe cases, doctors should also consider starting treatment for AIHA immediately to…
The presence of cold agglutinin disease (CAD) without red blood cells’ destruction in patients with COVID-19 should prompt clinicians to test for Mycoplasma pneumoniae, as this type of bacteria also is associated with CAD, a case report says. The study, “Cold agglutinin disease following…
The prevalence of cold agglutinin disease (CAD) is four times higher in colder climates than in warmer areas, according to a study from Europe. The findings also showed that a combination of rituximab with bendamustine is a safe and effective therapy for people with CAD. The study,…
Treatment with rituximab is safe and effective in managing autoimmune hemolytic anemia (AIHA), and seems to be more beneficial for people with warm antibody autoimmune hemolytic anemia (wAIHA) than for those with cold agglutinin disease (CAD), a review study has found. These findings indicate…
Heart surgery can be performed safely in people with cold agglutinin disease (CAD) by adopting a series of procedure adjustments, according to a case study. The study, “Cardiopulmonary bypass strategy in a patient with cold agglutinin of high thermal amplitude,” was published in the journal…
People with cold agglutinin disease (CAD) have genetic alterations previously reported in patients with marginal zone lymphoma (MZL), suggesting the disorders might be related, study reports. The study, “Cold agglutinin–associated B-cell lymphoproliferative disease shows highly recurrent gains of chromosome 3 and 12 or 18,” was…
Physicians have described the rare case of a woman with cold agglutinin disease (CAD) associated with advanced breast cancer. Her case was described in a case report study, “Cold autoimmune hemolytic anemia: a rare association with triple-positive breast cancer,” published in the Journal of…
T follicular helper cells, a subset of T-cells that help other immune cells produce antibodies, seem to play a role in the development of autoimmune hemolytic anemia (AIHA), a mouse study suggests. The study, “The Role of T Follicular Helper Cells and T Follicular Regulatory Cells in…
New targeted therapy options are needed for patients who develop autoimmune hemolytic anemia (AIHA) following a stem cell transplant, a review study says. The study, “Management of refractory autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation: current perspectives,” was published in the Journal of Blood Medicine. AIHA…
Get regular updates to your inbox.