Enjaymo (sutimlimab-jome) has been approved by the European Commission (EC) to treat anemia caused by the loss of red blood cells — called hemolytic anemia — in adults with cold agglutinin disease (CAD). The EC’s decision to approve the therapy, the first and only approved therapeutic option for…
A woman with cold agglutinin disease (CAD) secondary to a cancer also developed bilateral retinal vasculitis — inflammation of the blood vessels found at the back of both eyes — in what researchers claim to be “the first report of retinal vasculitis in a patient with CAD.” Initial treatment…
A woman developed cold agglutinin disease (CAD), with high levels of cold agglutinins sustained for four months after symptom onset following a third dose of a vaccine for SARS-CoV-2, the virus that causes COVID-19, a case report from Japan. According to its authors, “the present case indicates…
Cold agglutinin disease (CAD) patients who take Enjaymo (sutimlimab-jome) long term may continue to experience disease remission after treatment discontinuation, according to a small study of three female patients. Two of the three women — all treated with Enjaymo for at least three years — showed no…
An enterovirus infection triggered autoimmune hemolytic anemia (AIHA) — a condition in which the body’s immune system generates self-reactive antibodies that destroy red blood cells — in an 11-year-old boy, a case study has reported for the first time. Although some signs were consistent with a case of virus-induced…
Global Genes and RARE-X, two nonprofit organizations dedicated to improving the lives of people with rare diseases like cold agglutinin disease (CAD), announced they are joining forces, with the merger expected to close by the end of this year. “What was apparent to all of us was how closely…
Although extremely rare, there have been cases of cold agglutinin disease (CAD) and related conditions following vaccination against COVID-19, a recent review study reported. While it’s difficult to draw firm conclusions about cause and effect, scientists say developing CAD may be a very rare side effect from COVID-19 vaccines.
The rare disease patient advocacy organization Global Genes, along with the Rare Disease Diversity Coalition (RDDC), has launched the next phase of its partnership to advance health equity for people with rare conditions, such as cold agglutinin disease (CAD). The initiative Know Your Family History is focusing on the…
VV-ECMO, a technique used to deliver oxygen to the body when the lungs are not working properly, can be used in people with cold agglutinin disease (CAD) without notable complications, a case report shows. The report, “Veno-venous extra-corporeal membrane oxygenation in a COVID-19 patient with cold-agglutinin haemolytic anaemia:…
A committee of the European Medicines Agency has recommended Enjaymo (sutimlimab-jome) be approved for hemolytic anemia, or anemia due to the destruction of red blood cells, in adults with cold agglutinin disease (CAD). The positive opinion from the agency’s Committee for Medicinal Products for Human Use now will…
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