Patricia Inácio, PhD, science writer —

SARS-CoV-2, the virus that causes COVID-19, may trigger cold agglutinin disease (CAD) in children, a case report suggests. The report, “Autoimmune hemolytic anemia in children with COVID-19,” was published in the journal Pediatric Blood & Cancer. Autoimmune hemolytic anemia (AIHA), an autoimmune disease characterized by…

Ahead of this year’s Rare Disease Week on Capitol Hill, held virtually July 14–22, the EveryLife Foundation will award grants to top advocates of rare disease organizations who participate in the week’s pre-events. The top 50 point-earners will be eligible to win $1,000 to $5,000in  grants, totaling up…

Symptoms of cold agglutinin disease (CAD) worsened for a 57-year-old woman two days after receiving the first dose of a COVID-19 vaccine, and again two days after the second dose, a case study from Spain reported. In both instances, prednisone’s use eased her symptoms and restored normal values…

More than half of the people with rare diseases and their caregivers, asked in a survey, were undecided or less than willing to be vaccinated for COVID-19 if a vaccine was approved under emergency use authorization instead of the routine process, the EveryLife Foundation for Rare Disease reports. These findings…

The EveryLife Foundation for Rare Diseases is accepting applications for a scholarship program that aims to help adults with a rare disease pursue personal goals through training and education. For a second year, the #RAREis Scholarship Fund — supported by Horizon Therapeutics – will award 35 one-time scholarships, each…

COVID-19 can be associated with the development of cold agglutinin disease (CAD), leading to the need for blood transfusions. But the autoantibodies resulting from CAD may interfere with blood typing analyses needed for such transfusions, a case report found. The report, “Serological Blood Group Discrepancy and Cold…

Coronavirus disease 2019 (COVID-19) could cause cold agglutinin disease (CAD), a case report of two patients from France suggests. The cases were described in a letter to the editor of the journal Annals of Hematology. The letter, submitted by researchers from the University…

Japanese patients with cold agglutinin disease (CAD) are almost three times more likely to develop blood clots compared with people without this autoimmune disorder, a study reports. These findings are in agreement with the results for non-Asian populations, according to the researchers. The study, “Demographic characteristics, thromboembolism…

The risk of blood clots nearly doubles in people with cold agglutinin disease (CAD) compared with that seen in patients with other conditions, a large data study from the U.S. reports. “Increased risk of thrombotic events in cold agglutinin disease: A 10-year retrospective analysis” was published in the…

The autoantibodies found in people with cold agglutinin disease (CAD) carry high levels of sugar molecules, which may help distinguish them from those with related disorders, a study has found. The study, ““Glycosylation of Immunoglobulin Light Chains is Highly Prevalent in Cold Agglutinin Disease,” was published in…