Patricia Inácio, PhD, science writer —

A new case study reports the rare co-occurrence of cold agglutinin disease (CAD) and blood cancer in a man in Iran. The patient, 56, who had been diagnosed with myelodysplastic syndrome (MDS), an umbrella term for a group of rare blood cancers, was found to also have CAD…

A woman developed cold agglutinin disease (CAD), with high levels of cold agglutinins sustained for four months after symptom onset following a third dose of a vaccine for SARS-CoV-2, the virus that causes COVID-19, a case report from Japan. According to its authors, “the present case indicates…

Cold agglutinin disease (CAD) patients who take Enjaymo (sutimlimab-jome) long term may continue to experience disease remission after treatment discontinuation, according to a small study of three female patients. Two of the three women — all treated with Enjaymo for at least three years — showed no…

Fatigue is one of the most common symptoms of cold agglutinin disease (CAD), affecting 90% of patients, a U.S. survey found. Nearly half of people with the rare autoimmune disorder who responded to the survey, on the disease burden imposed by CAD, reported experiencing fatigue on a daily basis.

A total of 30 patient advocacy groups working to further understanding and the needs of people living with rare diseases have been selected to receive a Horizon Therapeutics‘ #RAREis Global Advocate Grant. Winners of this year’s inaugural awards are spread across nine countries and represent a total of 29 rare…

A middle-aged woman’s suddenly black fingertips and dark urine were telltale symptoms that she had developed cold agglutinin disease (CAD), according to scientists. Her case was described by a team of Japanese researchers in the study, “Black fingers and dark urine: cold agglutinin disease,”…

A 71-year-old woman with primary cold agglutinin disease (CAD) was successfully treated with the glucocorticoid prednisone, a case study reported. Its scientists noted that primary CAD typically does not respond to glucocorticoids, but in particular instances like this case, it can. The study, “A Case of Idiopathic Cold…

To help patients and families in the U.S. facing out-of-pocket medical costs, The Assistance Fund (TAF) has opened a new program for people living with cold agglutinin disease (CAD). This program is designed to provide financial assistance to eligible individuals with medical expenses for FDA-approved treatments, including treatment-related copayments, health…

Infection by SARS-CoV-2, the virus that causes COVID-19, may trigger cold agglutinin disease (CAD) in adults, according to a small systematic review. mRNa-based vaccines against SARS-CoV-2 were also shown to trigger CAD and other forms of autoimmune hemolytic anemia (AIHA), although only four cases were analyzed. Overall,…

Investment for rare diseases, such as cold agglutinin disease (CAD), has seen a growing interest by investors, outmatching that for biotech and other health segments, according to a recent analysis by Global Genes, a leading rare disease organization. During 2021, a total of $22.9 billion was raised for…