Cold agglutinin disease (CAD) is a rare autoimmune disease in which the immune system produces antibodies against the body’s own red blood cells. In cold temperatures, these antibodies bind tightly to these cells, causing them to clump together.
What is M. pneumoniae?
M. pneumoniae is a type of bacterium that commonly causes mild upper respiratory infections such as chest colds, sometimes called “walking pneumonia.”
In rare cases, it can also lead to pneumonia, which may require hospitalization, as well as increase the antibodies that cause CAD.
How does a M. pneumoniae infection cause CAD?
Cold agglutinin antibodies are normally produced in very low amounts by the immune system in response to an infection. It is unknown why some infections such as M. pneumoniae can cause a big increase in cold agglutinin antibodies, leading to CAD.
How are M. pneumoniae infections treated?
How can M. pneumoniae infections be prevented?
Like many respiratory infections, M. pneumoniae is spread by coughing and sneezing. Having had these infections previously does not make you less susceptible to the infection, so protect yourself by taking the following measures:
- Cover your mouth when you cough or sneeze.
- Wash your hands frequently and thoroughly (at least for 20 seconds) with soap and water.
- Avoid touching your eyes, nose, and face to prevent transmission of germs through your mucous membranes.
Last updated: Dec. 5, 2019
Cold Agglutinin Disease News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.