Diagnosis and treatment of cold agglutinin disease (CAD) secondary to a type of blood cancer was complicated by COVID-19 in a middle-aged man, a case study reports. The researchers identified specific mutations in immune cells that may explain the “treatment resistance and susceptibility to COVID-19,” they wrote in the…
Read more
I carefully pulled myself out of the sunken bathtub and waited a moment before swinging around to stand up. I gripped the sink next to me, pulled up, and caught my breath. “Whoa!” I thought to myself. “That tired me out. Good thing I don’t have to be at work…
A young woman in Colombia developed cold agglutinin disease (CAD) secondary to systemic lupus erythematosus (SLE), an autoimmune disease often called lupus, a study reports. While other types of autoimmune hemolytic anemia (AIHA) — rare autoimmune diseases marked by self-reactive antibodies attacking and destroying red blood cells —…
A student was waiting at my desk as I walked into the classroom. I smiled as I dropped my books on the desk and looked at her expectantly. She’d been absent the previous day. “Mrs. Lott, did we do anything while I was gone?” That was a stupid question. My…
Columnist Mary Lott tends to hear the same common questions about living with CAD, and she’s learned some lessons about how to answer them.
Check out Cold Agglutinin Disease News‘ collection of health insights, where you can find more information and guidance.
Click the link below to go to our FAQs page on cold agglutinin disease.
Cold agglutinin disease (CAD) is a rare disorder in which the immune system mistakenly attacks red blood cells, resulting in anemia.
CAD is characterized by autoantibodies, called cold agglutinins, binding to and activating the destruction of red blood cells when exposed to cold temperatures.
Symptoms of CAD include fatigue, Raynaud’s syndrome, joint pain, jaundice or skin discoloration, and heart problems. These symptoms can worsen with more cold exposure.
Get regular updates to your inbox.