A woman with cold agglutinin disease (CAD) who was misdiagnosed with and treated for a blood cancer achieved lasting health improvements once doctors switched her to Enjaymo (sutimlimab-jome), a case study shows. The woman had initially received therapies for chronic lymphocytic leukemia (CLL). However, those treatments failed to…
A 78-year-old woman with cold agglutinin disease (CAD) was later found to have acute myeloid leukemia (AML), a type of blood cancer, which likely caused the disease, according to a case study from the U.S. Doctors discovered the woman’s AML after her anemia continued to worsen despite signs that…
Discussion
A performance that stands out in my musical career is the Auburn High School versus Opelika High School football game of Nov. 14, 1969. It’s not the marching band’s musical skill that I recall, but that night’s extremely low temperatures. All our instruments were affected. A trombone player…
Cold agglutinin disease (CAD) rarely occurs without abnormal immune cell growth in the bone marrow or blood, but this abnormal cell growth is often hard to detect with standard assessments, a new study shows. “Our data underscore the importance of a comprehensive and sensitive approach when evaluating bone marrow…
Discussion
I parked my car with a feeling of déjà vu. This was my sixth trip to the hospital this year. I wanted to wait to be seen by my medical team, but my fever kept rising, so I decided to go to the emergency room. It was the first time…
Cold agglutinin disease (CAD) is a rare disorder in which the immune system mistakenly attacks red blood cells, resulting in anemia.
CAD is characterized by autoantibodies, called cold agglutinins, binding to and activating the destruction of red blood cells when exposed to cold temperatures.
Symptoms of CAD include fatigue, Raynaud’s syndrome, joint pain, jaundice or skin discoloration, and heart problems. These symptoms can worsen with more cold exposure.
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