An 83-year-old man with cold agglutinin disease (CAD) underwent surgery for an abdominal aortic aneurysm — a bulging in the lower part of the aorta, the body’s largest blood vessel — without major complications thanks to several preventive strategies, a study reported. To avoid complications from cold-induced hemolysis, or…
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Last summer, my right knee hurt. As far as I know there was no injury; it just hurt. The pain grew to the point where I hobbled around the house. I used food delivery services and generally babied my knee. Eventually, I went to my doctor. At the doctor’s office,…
An 83-year-old woman with cold agglutinin disease (CAD) had knee surgery under local spinal anesthesia without any disease-related complications as a result of significant warming strategies to prevent her body temperature from getting too low, a study shows. During and after the surgery, the woman’s body temperature remained stable…
“Round like a circle in a spiral, like a wheel within a wheel/ Never ending or beginning on an ever-spinning reel/… In the windmills of your mind.” When I try to figure out cold agglutinin disease (CAD), my mind goes round and round and never quite settles on one…
A woman in Taiwan likely developoed cold agglutinin disease (CAD) secondary to advanced diffuse large B-cell lymphoma (DLBCL), a type of fast-growing blood cancer that begins in immune B-cells, a study reports. This case adds to a growing, but still small, number of reports linking the two diseases. “We…
Cold agglutinin disease (CAD) is a rare disorder in which the immune system mistakenly attacks red blood cells, resulting in anemia.
CAD is characterized by autoantibodies, called cold agglutinins, binding to and activating the destruction of red blood cells when exposed to cold temperatures.
Symptoms of CAD include fatigue, Raynaud’s syndrome, joint pain, jaundice or skin discoloration, and heart problems. These symptoms can worsen with more cold exposure.
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